Active Substance: sildenafil
Common Name: sildenafil
ATC Code: G04BE03
Marketing Authorisation Holder: Pfizer Limited
Active Substance: sildenafil
Authorisation Date: 1998-09-14
Therapeutic Area: Impotence
Pharmacotherapeutic Group: Urologicals
Treatments for men with impotence problems, which can be not being able to achieve or maintain a penile erection sufficient for satisfactory heightened sexual performance.
In order that Generic Viagra Online to work, sexual stimulation is needed.
Generic Viagra On the internet is medicines that contains the active substance sildenafil. It is available as blue, diamond-shaped tablets (25, 50 or 100 mg).
Generic Viagra On the web is helpful to treat men with erection dysfunction (sometimes called impotence), when they cannot get or keep a challenging penis (erection) sufficient for satisfactory intercourse. For Generic Viagra Online to function, sexual stimulation is necessary.
The medicine is able to be obtained that has a prescription.
The recommended dose of Generic Viagra On the internet is 50 mg taken pro re nata about 60 minutes before sexual acts. If Generic Viagra On the web is taken with food, the onset of activity could possibly be delayed compared with taking Generic Viagra Online without food. The dose may be increased to a maximum of 100 mg or decreased to 25 mg according to the effectiveness and adverse reactions. Patients with liver problems or severe kidney problems should start treatment using the 25-mg dose. The ideal recommended dosing frequency is a tablet daily.
The active component in Generic Viagra Online, sildenafil, is owned by several medicines called phosphodiesterase-type-5 (PDE5) inhibitors. It works by blocking the phosphodiesterase enzyme, which normally reduces a substance referred to as cyclic guanosine monophosphate (cGMP). During normal sexual stimulation, cGMP is stated in the penis, where it causes posterior tibial muscle inside spongy tissue with the penis (the corpora cavernosa) to release, allowing the blood circulation into your corpora, producing the erection. By blocking the breakdown of cGMP, Generic Viagra Online restores erectile function. Sexual stimulation is were required to produce a hardon.
Generic Viagra Online has become studied in four main studies including 1,690 men aged 19 to 87 years, where rrt had been in comparison with placebo (a dummy treatment) for between 12 and 26 weeks. Two of these studies used fixed doses (patients allotted to 25, 50 or 100 mg) and a couple of studies were flexible (patients began on 25 mg and can be gone to 50 or 100 mg based on their response). Furthermore, there initially were studies in patients with spinal-cord injury with diabetes. The main measure of effectiveness took it's origin from the capability of your men for getting and gaze after a harder erection. It was recorded within a special questionnaire completed in your own home using a rating system using a five-point scale, the place where a score of 5 represents the very best result.
Generic Viagra Online was much more effective than placebo in all studies. Inside the questionnaire, scores for the question on what usually the patient could achieve intercourse went from about 2 with no treatment to 3 or 4 with Generic Viagra Online 50 mg. Within the fixed-dose studies, the proportions of patients reporting that treatment improved their erections were 62% (25 mg), 74% (50 mg) and 82% (100 mg), compared with 25% on placebo.
The commonest side effect with Generic Viagra Online (seen in greater than 1 patient in 10) is headache. For that full listing of all negative effects reported with Generic Viagra Online, start to see the package leaflet
Generic Viagra Online shouldn't be used in folks who might be hypersensitive (allergic) to sildenafil or some of the other ingredients, or where sex activity is inadvisable (e.g. men with severe heart problems just like unstable angina or severe coronary failure). It should also not taken by patients who've ever endured diminished vision due to a trouble with blood flow on the nerve while in the eye (non-arteritic anterior ischaemic optic neuropathy or NAION). Generic Viagra Online should not be taken with nitrates (medicines familiar with treat angina). Because Generic Viagra Online will never be studied in patients with severe liver disease, hypotension (low hypertension), recent stroke or myocardial infarction (cardiac arrest), or maybe a hereditary eye disease, for example retinitis pigmentosa, these patients should not use it.
The Committee for Medicinal Products for Human Use (CHMP) decided that Generic Viagra Online s benefits are greater than its risks to the management of men with erectile dysfunction. The Committee recommended that Generic Viagra Online have access to marketing authorisation.
The European Commission granted a marketing authorisation valid in the European for Generic Viagra Online to Pfizer Limited on 14 September 1998. The marketing authorisation was renewed on 14 September 2003 and on 14 September 2008.
Source: European Medicines Agency
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